The ONGOING Phase 3 Clinical Trials Of The Pfizer mRNA 'Vaccine' Just Threw Up A Very Surprising And Somewhat Disturbing Result
Jessica Rose just published this fascinating and very important Stack today:
It makes for fascinating, if somewhat disturbing reading. Rather than highlight what Jessica is saying, which I strongly suggest you read, I went through the actual study myself, which she cites, and there’s a few points of my own which I’d like to highlight, arising from the findings of that study, which I think are vitally important to get across, because they prove beyond doubt that the mRNA mass vaccinations have been an experiment upon humanity, which is currently ongoing and is throwing up some surprising, disturbing and highly unusual results. Yes, you are a human guinea pig if you took part in these trials and no, you were not provided with the opportunity to give your full, informed consent prior to doing so. The Nuremberg Code, and hence basic human rights, were violated on a massive scale. Josef Mengele’s evil Ghost went global in 2021 and 2022.
So here goes:
Shortly after the initial two mRNA vaccine doses, the IgG response mainly consists of the pro-inflammatory subclasses IgG1 and IgG3. Here, we report that several months after the second vaccination, SARS-CoV-2-specific antibodies were increasingly composed of non-inflammatory IgG4, which were further boosted by a third mRNA vaccination and/or SARS-CoV-2 variant breakthrough infections. IgG4 antibodies among all spike-specific IgG antibodies rose on average from 0.04% shortly after the second vaccination to 19.27% late after the third vaccination. This induction of IgG4 antibodies was not observed after homologous or heterologous SARS-CoV-2 vaccination with adenoviral vectors.
So, surprisingly, non-inflammatory IgG4 antibodies started appearing in large numbers several months after the second jab and their numbers were boosted by a third jab, or a ‘breakthrough’ infection. Vaccination is not supposed to do this; it’s supposed to boost your cytotoxic, pro-inflammatory IgG1 and IgG3 antibodies, which rapidly clear the viral infection from your system.
Importantly, this class switch was associated with a reduced capacity of the spike-specific antibodies to mediate antibody-dependent cellular phagocytosis and complement deposition.
This is not a normal response for a vaccine - perhaps because Pfizer isn’t a ‘vaccine’?
Shortly after the administration of two doses of SARS-CoV-2- mRNA vaccine (either Comirnaty or mRNA-1273), IgG1 and IgG3 were found to be the predominant IgG subclasses, whereas IgG2 responses were rare and IgG4 responses almost undetectable (23, 24). However, the longitudinal evolution of all four IgG subclasses (IgG1, 2, 3 and 4) in response to mRNA vaccination – and particularly their long-term development after the second and the third dose – has not yet been analyzed.
Until now. They analysed it in these health care workers. They found a highly unusual class-switch to IgG4 antibodies, not characteristic of other vaccinations or viral infections.
The IgG4 subclass does not prevail after repeated vaccination with tetanus toxoid or respiratory syncytial virus infection
Generally, IgG4 responses have been rarely observed even after repeated immunizations or infections.
These findings support the notion that class-switching to IgG4 is not a general consequence of repeated antigen exposure in form of vaccinations or infections.
Furthermore, the elevated levels of IgG4 antibodies correlate highly with the appearance of ‘breakthrough’ infections. It’s not clear whether this is cause or effect but the researchers demonstrate conclusively that the class-switch to IgG4 corresponds to a drop in neutralising capacity, which naturally implies that the vaccinated person is more susceptible to infection. In fact, no breakthrough infections occurred prior to the observed increases in IgG4:
Notably, a marked increase in IgG4 antibody levels was observed after the booster immunization in nearly all vaccinees. Until this time point, none of the participants reported an episode of SARS-CoV-2 infection and we could also not detect anti-nucleoprotein antibodies in any of the serum samples.
So it’s not unreasonable to suppose that IgG4 antibodies start appearing several months after the second dose, they are boosted by the third dose, which results in breakthrough infections, which themselves further boost the levels of IgG4. A positive feed-back loop - except it’s not that positive.
Addendum
On a final note, the researchers did not find that the adenoviral vector produced this curious effect, so concluded that it must have something to do with the presence of the mRNA itself, not the spike protein:
Furthermore, we observed significantly higher IgG4 levels after two doses of Comirnaty mRNA vaccine compared to a heterologous immunization regimen with a primary Vaxzevria vaccination followed by one dose of Comirnaty, although the total anti-spike IgG response was comparable. This argues against the hypothesis that repeated exposure to the spike protein itself triggers the unusual IgG4 response. It is currently not clear whether or to what extent the Comirnaty mRNA vaccination or the short interval of immunizations are responsible for the observed long-lasting GC reactions (12–14), but a prolonged presence of vaccine mRNA or antigen in the lymph node might be a potential explanation (12).
Does this have implications for pregnant women who have been boosted? According to the wikipedai page on IgG:
"IgG is secreted as a monomer that is small in size allowing it to easily perfuse tissues. It is the only antibody isotype that has receptors to facilitate passage through the human placenta, thereby providing protection to the fetus in utero. Along with IgA secreted in the breast milk, residual IgG absorbed through the placenta provides the neonate with humoral immunity before its own immune system develops. Colostrum contains a high percentage of IgG...
Therefore, in the first six months of life, the newborn has the same antibodies as the mother and the child can defend itself against all the pathogens that the mother encountered in her life (even if only through vaccination) until these antibodies are degraded. This repertoire of immunoglobulins is crucial for the newborns who are very sensitive to infections, especially within the respiratory and digestive systems.
It makes a person wonder what this looks like in people that have had two doses, two boosters, the bi-valent booster, and one or more breakthrough infections.